Brian’s first cousin was married this weekend. It was great to see his grandfather (Pa) again and meet some other family members.
|Brian and his Grandfather (Pa)|
|Uncle Eric, Brian and Pa|
|Aunt Maria, Cousin Jacklyn, Uncle Eric|
|Aunt Maria, Twins – Cousin Crystal and Jacklyn|
|Mother Son Dance|
|Listening to the best man’s speech|
|Brian and I with the newlyweds|
I’ve been trying to get to the root of my Meniere’s Disease. As I’ve stated before, there is no known cause or cure for the disease but many have found some relief from symptoms through different methods. I’ve tried almost all methods except the antiviral method and I have also not yet been tested for candida overgrowth.
My ENT doctor was unwilling to listen when I talked about doing an antiviral method so I contacted my family doctor and she is willing to try it. It starts as a high dose and tapers down to a maintenance dose. I had to get blood work done before starting the regimen. The blood work is to get a baseline for kidney function as the long term use of the antiviral medicine can cause kidney issues. I will then have to get regular blood monitoring every two months.
I’m sharing this information for anyone else who may be suffering from this disease. Below is the letter I sent to my doctor along with links to the medical studies. If you are suffering from this I highly suggest sending your doctor this letter along with a printed copy of both medical articles a week or two prior to your appointment so they have time to review it before your appointment. Once the doctor received my letter she called me to set up a 30 minute appointment to discuss.
Links to the medical studies I’ve referenced in the letter to my doctor below.
Dr. Gracek’s Article – HERE
Autoimmune Condition Article – HERE
Sorry for not getting this information to you sooner. Just this morning I was able to secure an appointment for tomorrow afternoon to discuss my Meniere’s Disease, Bell’s palsy and an active cold sore.
Read closely the information on P. 103, for effective dosages and durations. Dr. Gracek gains an 88% to 90% complete relief of Meniere’s symptoms with his protocols, described in the paper.
For your information — here’s the cogent treatment text. I’ve taken the liberty to highlight crucial information:
The antiviral treatment protocol for patients with recurrent vertigo is as indicated below.
Discontinue all previous medical treatments; ensure that patients are cleared for normal
renal and liver function; use acyclovir tabs 800 mg t.i.d. for 3 weeks and reexamine. If there
is significant relief of vertigo, decrease to 800 mg b.i.d. for 3 weeks, then to 800 mg daily as a
maintenance dose. If valacyclovir is selected (in those who fail to respond to acyclovir), use
1 g t.i.d. for 3 weeks with taper to b.i.d. for a further 3 weeks and then 1 g daily as a maintenance
dose. The starting dose of acyclovir was given for a longer period (3 weeks) than that
used for zoster because it was felt necessary to cross the blood-brain barrier to reach ganglion
and satellite cells with virus. Most patients experienced relief from vertigo in the first 2 weeks
but some required a longer period. The gradual lowering dose was then used to find the
lowest level maintenance dose for a given patient. Most were controlled on a single dose daily
but occasionally a patient required an adjustment to 1,200 mg of acyclovir or 1,500 mg of
These dosages may require adjustment in patients with impaired kidney or liver function.
The follow-up period was as short as 3 years in the most recent patients and 8 years in the
earliest patients in the series. Of 106 patients with VN (the earliest patients evaluated up to
8 years), 93 (88%) had complete relief of symptoms with oral acyclovir, 54 of 60 patients
(90%) with MD [Meniere's disease] were relieved of vertigo, and 27 of 45 patients (60%) with posterior canal
BPPV were relieved of symptoms. Between the use of antivirals and repositioning maneuvers
(physical therapy), the number of chronically disabled patients who were candidates for
ablation of posterior semicircular canal function (canal occlusion or singular neurectomy)
was reduced significantly.
As a result of these morphological and clinical observations, our approach to the patient
with recurrent vertigo has been simplified. It goes without saying that the patient without
recurrent balance symptoms needs no further treatment after a hearing test and MRI of the
brain (assuming that these are normal). A Hallpike maneuver is included in the initial examination.
Those patients with recurrent vertigo are offered a trial of oral acyclovir (or Valtrex)
for 3 weeks.
Examination at the 3-week period will determine the sensitivity of the particular NT
virus to the antiviral. If there is no relief of vertigo with acyclovir or valacyclovir, treatment
is followed by vestibular tests (videonystagmography and vestibular-evoked myogenic
potential) to determine the responsible ear. If these results are abnormal chemical labyrinthotomy
is offered. The patient is offered a choice between dexamethasone (12 mg/ml) or
gentamycin (80 mg/2 ml), considering the risk of hearing loss (dexamethasone 0%; gentamycin
usually negligible if used in a single small dose).
“Recently, direct evidence of viral neuropathy in Meniere’s disease has been provided by the transmission electron microscopic observation of viral structures in vestibular ganglion cells excised from a patient with Meniere’s disease (Picture 3 and Picture 4)  and . The clinical response to antiviral medication indicated that vertigo due to Meniere’s disease was relieved in 85–90% of patients. It is not surprising that control of vertigo was not greater than 85–90%, as mutant strains of the herpes virus group would be resistant to the acyclovir class of antivirals. Until newer antivirals are developed, approximately 10% of Meniere’s disease patients with vertigo will not be controlled. The auditory symptoms are less effectively treated by the antiviral approach because loss of hair cells and spiral ganglion cells secondary to the toxicity of viral proteins in the perilymph is not reversible.”
“The antiviral approach to the very common disabling balance symptoms experienced by patients with Meniere’s disease has virtually eliminated the use of various surgical methods used in the past. These include labyrinthectomy, endolymphatic sac decompression and vestibular nerve transection. The high (90%) rate of vertigo control with orally administered antivirals should be considered as a frontline treatment for vertigo.”
Meniere’s disease is an autoimmune disorder. Its etiopathogenesis includes viral infection. The histopathological correlate of Meniere’s disease is endolymphatic hydrops and vestibular endorgans demonstrates variable degrees of neuroepithelial degeneration
Due to the possible autoimmune pathogenesis of the disease, pharmacotherapy for Meniere’s disease may include corticosteroids, etanercept and warfarin. The use of antiviral agents corresponds to the viral hypothesis and has eliminated the various surgical methods of the past.
Gene therapy could be used in the future to transfer genetic material into inner ear cells using viral vectors and to protect, rescue, and even regenerate hair cells of the inner ear
This week Addison attended her first “Paws to Read” session. Our local library offers this program for beginning readers to build their confidence by reading to dogs from the Humane Society. Thanks Mom for taking her!
Enzo is obsessed with bull riding. Every time he watches the iPad his first request is “Find Angry Bulls.” The rodeo was in Jacksonville over the weekend so we surprised him. He loved every second of it. He’s been role playing it every day since
Our Breezy Beach Life
|Making ice cream|
|Enjoying the ice cream they made|
Dibs to Wind-NC‘s Andy McKinney who made it out to the AWT Goya Cabo Verde Pro and scored great conditions and an awesome time with the AWT family of top world renowned wavesailors! Great to see all the stoke and the action as it unfolded though the numerous Facebook posts and commentary as the event unfolded.
Check out the tour stop wrap video!
Next stop on the AWT is Santa Cruz, CA June 4-7, 2015. Of course, AWT Hatteras Wave Jam is Sept 21-26, 2015!
Bill’s OBX Beach Life